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Peripheral administration of exendin-4 [691] or direct administration of GLP-1 into the core of the NAcc [744] increases cFos expression in this region, and direct activation of NAcc GLP-1R reduces food intake while its direct inhibition by exendin (9–39) induces hyperphagia [744]
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Liraglutide injection 0.6 mg is not effective for glycemic control and is intended only as a starting dose to reduce gastrointestinal intolerance [see Dosage and Administration (2)]
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